Survival and persistence of Bacillus clausii in the human gastrointestinal tract following oral administration as spore-based probiotic formulation
نویسندگان
چکیده
منابع مشابه
Safety assesment of Bacillus clausii UBBC07, a spore forming probiotic
Probiotics are vital bacteria that colonize the intestine and modify its microflora with benefits for the host. Very few members of the Bacillus group are recognized as safe for use and hence only a few strains are available as commercial preparations for application in humans and animals. Acute and subacute studies in rats were conducted to establish safety of Bacillus clausii (B. clausii) UBB...
متن کاملBacillus probiotics: spore germination in the gastrointestinal tract.
Spores of Bacillus species are being used commercially as probiotics and competitive exclusion agents. Unlike the more commonly used Lactobacillus-type probiotics, spores are dormant life forms. To address how spore probiotics might function we have investigated whether spores can germinate in the gastrointestinal tract by using a murine model. Using a genetically engineered chimeric gene, ftsH...
متن کاملDraft Genome Sequence of Bacillus clausii UBBC07, a Spore-Forming Probiotic Strain.
ITALIC! Bacillus clausiiUBBC07 is a safe endospore-forming strain, characterized for defined therapeutic effects. The finished draft whole-genome sequence is presented here to scan its genetic constitution for its expanded use as a probiotic in various health sectors.
متن کاملBacillus clausii probiotic strains: antimicrobial and immunomodulatory activities.
The clinical benefits observed with probiotic use are mainly attributed to the antimicrobial substances produced by probiotic strains and to their immunomodulatory effects. Currently, the best-documented probiotic bacteria used in human therapy are lactic acid bacteria. In contrast, studies aiming to characterize the mechanisms responsible for the probiotic beneficial effects of Bacillus are ra...
متن کاملEffect of long-term oral administration of thyroxine on morphology of the gastrointestinal tract in broiler breeder hens
Published data on 4-week-long administration of extra thyroxine (T4) in broiler breeder hens to alleviate the cold-induced ascites in their offspring suggested that long-term maternal hyperthyroidism would affect the gastrointestinal tract morphology. Broiler breeder hens (n=70) were reared in individual cages and allotted to control and hyperthyroid groups (five replicates of seven ...
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ژورنال
عنوان ژورنال: Journal of Applied Microbiology
سال: 2015
ISSN: 1364-5072
DOI: 10.1111/jam.12848